Brain injury due to anaphylactic shock: broadening manifestations of Kounis syndrome , Abstract In the report published in this Journal (Ding et al. 2013), a 45-year-old woman with a history of allergy to ceftriaxone developed anaphylactic shock 10 minutes after application of a formocresol (formaldehyde cresol and phenolic protein-coagulating compound) soaked cotton pellet in the pulp chamber with zinc phosphate cement. She developed signs of hypersensitivity including dizziness, shortness of breath, nausea and lost consciousness while her systolic blood pressure dropped to 60 mm Hg. She consequently was treated with epinephrine, corticosteroids and intravenous infusion of 5% dextrose. The patient regained consciousness after 23 min. However, after regaining consciousness, she began complaining of a headache which increased in severity over time. Her blood pressure returned to normal 4 h after she lost consciousness. Magnetic resonance imaging revealed hyperintensity on T2-weighted imaging and hypointensity on T1-weighted imaging, corresponding to swelling of the gyrus in the cerebral watershed territory of the left parietal–occipital lobe. The patient was diagnosed with brain injury due to anaphylactic shock caused by formocresol. Traditionally, formocresol and related agents are used as disinfectants for root canal treatment, pulpotomy and root canal sealants. This article is protected by copyright. All rights reserved. , http://bit.ly/18UMMLV

Brain injury due to anaphylactic shock: broadening manifestations of Kounis syndrome , Abstract In the report published in this Journal (Ding et al. 2013), a 45-year-old woman with a history of allergy to ceftriaxone developed anaphylactic shock 10 minutes after application of a formocresol (formaldehyde cresol and phenolic protein-coagulating compound) soaked cotton pellet in the pulp chamber with zinc phosphate cement. She developed signs of hypersensitivity including dizziness, shortness of breath, nausea and lost consciousness while her systolic blood pressure dropped to 60 mm Hg. She consequently was treated with epinephrine, corticosteroids and intravenous infusion of 5% dextrose. The patient regained consciousness after 23 min. However, after regaining consciousness, she began complaining of a headache which increased in severity over time. Her blood pressure returned to normal 4 h after she lost consciousness. Magnetic resonance imaging revealed hyperintensity on T2-weighted imaging and hypointensity on T1-weighted imaging, corresponding to swelling of the gyrus in the cerebral watershed territory of the left parietal–occipital lobe. The patient was diagnosed with brain injury due to anaphylactic shock caused by formocresol. Traditionally, formocresol and related agents are used as disinfectants for root canal treatment, pulpotomy and root canal sealants. This article is protected by copyright. All rights reserved. , http://bit.ly/18UMMLV , via Dental Teach " Daily Dental Info " http://www.facebook.com/photo.php?fbid=619101624781057&set=a.582976205060266.1073741849.110664842291407&type=1